Lignans from Santalum album and Their Cytotoxic Activities
نویسندگان
چکیده
منابع مشابه
Lignans from Santalum album and their cytotoxic activities.
A new neolignan, (7R,8R)-5-O-demethylbilagrewin (1), together with four known lignans (2-5), were isolated from the heartwood of Santalum album (Santalaceae). The structure of 1 was determined by analysis of extensive spectroscopic data. The isolated compounds and derivatives were evaluated for their cytotoxic activities against HL-60 human promyelocytic leukemia cells and A549 human lung adeno...
متن کاملα-Santalol derivatives from Santalum album and their cytotoxic activities.
A bioassay-guided fractionation of the heartwood of Santalum album led to the isolation of seven α-santalol derivatives including (9S,10E)-9-hydroxy-α-santalal, (10R,11S)-10,11-dihydroxy-α-santalol, (9E)-11,13-dihydroxy-α-santalol, and (10E)-12-hydroxy-α-santalic acid. Their structures were determined on the basis of results of spectroscopic analysis, including two-dimensional (2D) NMR spectros...
متن کاملAntifungal and Ichthyotoxic Sesquiterpenoids from Santalum album Heartwood.
In our continuing study on a survey of biologically active natural products from heartwood of Santalum album (Southwest Indian origin), we newly found potent fish toxic activity of an n-hexane soluble extract upon primary screening using killifish (medaka) and characterized α-santalol and β-santalol as the active components. The toxicity (median tolerance limit (TLm) after 24 h at 1.9 ppm) of α...
متن کاملCytotoxic sesquiterpenes and lignans from Saussurea deltoidea.
Two new sesquiterpenes deltoiden A (1) and deltoiden B (2), and two new lignans deltoignan A (9) and deltoignan B (10), together with 14 known compounds, including six sesquiterpenes 3-8 and three lignans 11-13, were isolated from the whole plant of Saussurea deltoidea. Compounds 3-8 and 11-17 were isolated for the first time from this plant. Their structures were established by spectroscopic a...
متن کاملImmunopharmacological screening of aqueous root extract of Santalum album
Gupta A and Chaphalkar SR Journal of HerbMed Pharmacology, Volume 5, Number 1, January 2016 http://www.herbmedpharmacol.com 8 Actually, this plant is being exploited for various purposes especially sandalwood oil is obtained mostly by steam distillation of its root and heartwood (8,9) with a number of medicinal uses e.g. treatment of many other ailments like diarrhea along with bleeding, intrin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2010
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.58.587